CIDEA 抗体
Quick Overview for CIDEA 抗体 (ABIN7112559)
抗原
See all CIDEA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- CIDEA antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- cell death-inducing DFFA-like effector a
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))
-
别名
- CIDEA
-
背景
-
Synonyms: Lipid transferase CIDEA|Cell death activator CIDE-A|Cell death-inducing DFFA-like effector A|CIDEA
Background: Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter(By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.
-
分子量
- 25 kDa
-
基因ID
- 1149
-
UniProt
- O60543
抗原
-