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CIDEA 抗体

This anti-CIDEA antibody is a 兔 多克隆 antibody detecting CIDEA in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7112559
发货至: 中国

Quick Overview for CIDEA 抗体 (ABIN7112559)

抗原

See all CIDEA 抗体
CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

适用

人, 小鼠, 大鼠

宿主

  • 45
  • 3
  • 1

克隆类型

  • 48
  • 1
多克隆

标记

  • 26
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CIDEA antibody is un-conjugated

应用范围

  • 29
  • 20
  • 13
  • 13
  • 9
  • 8
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 原理

    CIDEA antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    cell death-inducing DFFA-like effector a

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

    别名

    CIDEA

    背景

    Synonyms: Lipid transferase CIDEA|Cell death activator CIDE-A|Cell death-inducing DFFA-like effector A|CIDEA

    Background: Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter(By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.

    分子量

    25 kDa

    基因ID

    1149

    UniProt

    O60543
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