CD8 alpha 抗体
Quick Overview for CD8 alpha 抗体 (ABIN7112517)
抗原
See all CD8 alpha (CD8A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD8A antibody
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纯化方法
- protein A+G purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- CD8a molecule
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亚型
- IgG1
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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别名
- CD8A
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背景
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Synonyms: T-cell surface glycoprotein CD8 alpha chain|T-lymphocyte differentiation antigen T8/Leu-2|CD8A|MAL
Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 30 kDa
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基因ID
- 925
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UniProt
- P01732
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途径
- TCR Signaling
抗原
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