CRADD 抗体
Quick Overview for CRADD 抗体 (ABIN7112351)
抗原
See all CRADD 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CRADD antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- CASP2 and RIPK1 domain containing adaptor with death domain
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亚型
- IgG
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anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibody
CRADD 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) antibodyCRADD 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) antibodyCRADD 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD 适用: 人 WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal AT14G8 unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 99-117), (Middle Region) antibodyCRADD 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal 23# unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
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别名
- CRADD
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背景
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Synonyms: Death domain-containing protein CRADD|Caspase and RIP adapter with death domain|RIP-associated protein with a death domain|CRADD|RAIDD
Background: RAIDD, also named as CRADD, is an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. CRADD interacts with BCL10 through its caspase recruitment domain and suppresses interactions between BCL10 and CARMA1. It is a negative regulator of the CARMA1 signalosome and suppressor of Th1-and Th17-mediated inflammatory responses.
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分子量
- 23 kDa
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UniProt
- P78560
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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