CRADD 抗体
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- 抗原 See all CRADD 抗体
- CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CRADD antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- CASP2 and RIPK1 domain containing adaptor with death domain
- 亚型
- IgG
- Top Product
- Discover our top product CRADD Primary Antibody
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anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibody
CRADD 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) antibodyCRADD 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) antibodyCRADD 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal 23# unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) antibody (HRP)CRADD 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
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- 应用备注
- WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:20-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
- 别名
- RAIDD (CRADD 产品)
- 背景
- Synonyms:CRADD, RAIDD Background:RAIDD, also named as CRADD, is an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. CRADD interacts with BCL10 through its caspase recruitment domain and suppresses interactions between BCL10 and CARMA1. It is a negative regulator of the CARMA1 signalosome and suppressor of Th1-and Th17-mediated inflammatory responses.
- 分子量
- 23 kDa
- UniProt
- P78560
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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