CASQ2 抗体
Quick Overview for CASQ2 抗体 (ABIN7112233)
抗原
See all CASQ2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- CASQ2 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- calsequestrin 2(cardiac muscle)
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- CASQ2 (Calsequestrin 2 (CASQ2))
-
别名
- CASQ2
-
背景
-
Synonyms: Calsequestrin-2|Calsequestrin, cardiac muscle isoform|CASQ2
Background: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2, this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.
-
分子量
- 55 kDa
-
UniProt
- O14958
-
途径
- Negative Regulation of Transporter Activity
抗原
-