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CALCOCO2 抗体

CALCOCO2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7112166
发货至: 中国
  • 抗原 See all CALCOCO2 抗体
    CALCOCO2 (Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2))
    适用
    • 26
    • 4
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 18
    • 9
    克隆类型
    • 20
    • 7
    多克隆
    标记
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CALCOCO2 antibody is un-conjugated
    应用范围
    • 20
    • 9
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    calcium binding and coiled-coil domain 2
    亚型
    IgG
    Top Product
    Discover our top product CALCOCO2 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    CALCOCO2 (Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2))
    别名
    CALCOCO2 (CALCOCO2 产品)
    别名
    CALCOCO2 antibody, MGC110205 antibody, wu:fj08c01 antibody, zgc:110205 antibody, DKFZp469D2219 antibody, NDP52 antibody, 2410154J16Rik antibody, C77254 antibody, Ndp52 antibody, Ndp52l1 antibody, RGD1559974 antibody, calcium binding and coiled-coil domain 2 antibody, CALCOCO2 antibody, calcoco2 antibody, Calcoco2 antibody
    背景
    Synonyms:NDP52 Background:Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation. Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens such as Salmonella typhimurium upon entry into the cytosol by targeting galectin-8-associated bacteria for autophagy(PubMed:22246324). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation(PubMed:23022382, PubMed:25771791). Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C(PubMed:23022382, PubMed:25771791). May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion(PubMed:17635994).
    分子量
    52 kDa
    基因ID
    10241
    UniProt
    Q13137
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