CALCOCO2 抗体 (Internal Region)
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- 抗原 See all CALCOCO2 抗体
- CALCOCO2 (Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CALCOCO2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 特异性
- CALCOCO2 Antibody detects endogenous levels of total CALCOCO2.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CALCOCO2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CALCOCO2 Primary Antibody
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anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 137-446) antibody
CALCOCO2 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 347-446) antibodyCALCOCO2 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) antibodyCALCOCO2 适用: 人, 大鼠, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 1-446) antibodyCALCOCO2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 347-446) antibodyCALCOCO2 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 1-446) antibodyCALCOCO2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 137-446) antibodyCALCOCO2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) antibodyCALCOCO2 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CALCOCO2 (Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2))
- 别名
- CALCOCO2 (CALCOCO2 产品)
- 别名
- CALCOCO2 antibody, MGC110205 antibody, wu:fj08c01 antibody, zgc:110205 antibody, DKFZp469D2219 antibody, NDP52 antibody, 2410154J16Rik antibody, C77254 antibody, Ndp52 antibody, Ndp52l1 antibody, RGD1559974 antibody, calcium binding and coiled-coil domain 2 antibody, CALCOCO2 antibody, calcoco2 antibody, Calcoco2 antibody
- 背景
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Description: Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation. Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens such as Salmonella typhimurium upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (PubMed:22246324). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation (PubMed:23022382, PubMed:25771791). Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C (PubMed:23022382, PubMed:25771791). May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion (PubMed:17635994).
Gene: CALCOCO2
- 分子量
- 52 kDa
- 基因ID
- 10241
- UniProt
- Q13137
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