CALCOCO2 抗体
Quick Overview for CALCOCO2 抗体 (ABIN7112166)
抗原
See all CALCOCO2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- CALCOCO2 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- calcium binding and coiled-coil domain 2
-
亚型
- IgG
-
-
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 137-446) antibody
CALCOCO2 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 347-446) antibodyCALCOCO2 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) antibodyCALCOCO2 适用: 人, 大鼠, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 1-446) antibodyCALCOCO2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 347-446) antibodyCALCOCO2 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 1-446) antibodyCALCOCO2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (Internal Region) antibodyCALCOCO2 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 137-446) antibodyCALCOCO2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) antibodyCALCOCO2 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:50-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- CALCOCO2 (Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2))
-
别名
- CALCOCO2
-
背景
-
Synonyms: Calcium-binding and coiled-coil domain-containing protein 2|Antigen nuclear dot 52 kDa protein|Nuclear domain 10 protein NDP52 (Nuclear domain 10 protein 52)|Nuclear dot protein 52|CALCOCO2|NDP52
Background: Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation. Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens such as Salmonella typhimurium upon entry into the cytosol by targeting galectin-8-associated bacteria for autophagy(PubMed:22246324). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation(PubMed:23022382, PubMed:25771791). Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C(PubMed:23022382, PubMed:25771791). May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion(PubMed:17635994).
-
分子量
- 52 kDa
-
基因ID
- 10241
-
UniProt
- Q13137
抗原
-
