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N-Cadherin 抗体

This anti-N-Cadherin antibody is a 小鼠 单克隆 antibody detecting N-Cadherin in WB, IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7112147
发货至: 中国

Quick Overview for N-Cadherin 抗体 (ABIN7112147)

抗原

See all N-Cadherin (CDH2) 抗体
N-Cadherin (CDH2) (Cadherin 2 (CDH2))

适用

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人, 小鼠, 大鼠

宿主

  • 102
  • 57
  • 4
  • 2
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  • 1
小鼠

克隆类型

  • 93
  • 74
  • 1
单克隆

标记

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This N-Cadherin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

1G1
  • 纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    cadherin 2, type 1, N-cadherin(neuronal)

    亚型

    IgG2a
  • 应用备注

    WB: 1:1000-1:10000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    N-Cadherin (CDH2) (Cadherin 2 (CDH2))

    别名

    N-cadherin

    背景

    Synonyms:Cadherin 2, CD325, CDH2, CDHN, CDw325, N cadherin, NCAD, N-cadherin, Neural cadherin Background:Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density(By similarity).

    分子量

    130 kDa

    基因ID

    1000

    UniProt

    P19022

    途径

    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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