BBS9 抗体
Quick Overview for BBS9 抗体 (ABIN7111939)
抗原
See all BBS9 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- Bardet-Biedl syndrome 9
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亚型
- IgG
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anti-Bardet-Biedl Syndrome 9 (BBS9) (AA 8-185) antibody
BBS9 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 9 (BBS9) (AA 244-320) antibodyBBS9 适用: 大鼠 ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 9 (BBS9) (AA 1-310) antibodyBBS9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:6000, IP: 1:500-1:3000, IHC: 1:50-1:500, IF: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- BBS9 (Bardet-Biedl Syndrome 9 (BBS9))
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别名
- BBS9
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背景
- Synonyms:PTHB1 Background:The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.
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分子量
- 60 kDa
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基因ID
- 27241
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UniProt
- Q3SYG4
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途径
- Hedgehog Signaling
抗原
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