BBS4 抗体
Quick Overview for BBS4 抗体 (ABIN7111934)
抗原
See all BBS4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- BBS4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- Bardet-Biedl syndrome 4
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亚型
- IgG
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anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 350-519) antibody
BBS4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-519) antibodyBBS4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 431-519) antibodyBBS4 适用: 小鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-240) antibodyBBS4 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 1292CT845-130-218 unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (N-Term) antibodyBBS4 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, Pig, 兔, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 125-139) antibodyVerified BBS4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 33-46) antibodyVerified BBS4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-519) antibodyBBS4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 215-264) antibodyBBS4 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 兔, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 71-120) antibodyBBS4 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
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别名
- BBS4
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背景
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Synonyms: Bardet-Biedl syndrome 4 protein|BBS4
Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog(SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization. Required for microtubule anchoring at the centrosome but not for microtubule nucleation. May be required for the dynein-mediated transport of pericentriolar proteins to the centrosome.
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分子量
- 50-60 kDa
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基因ID
- 585
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UniProt
- Q96RK4
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途径
- Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
抗原
-
