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ATG12 抗体

This 兔 多克隆 anti-ATG12 antibody specifically detects ATG12 in WB, IHC, ELISA 和 IP. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7111887
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ATG12 抗体 (ABIN7111887)

抗原

See all ATG12 抗体
ATG12 (Autophagy Related 12 (ATG12))

适用

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人, 小鼠

宿主

  • 98
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克隆类型

  • 67
  • 52
多克隆

标记

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This ATG12 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 原理

    ATG12 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    ATG12 autophagy related 12 homolog

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:500-1:2000 , IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    ATG12 (Autophagy Related 12 (ATG12))

    别名

    ATG12

    背景

    Synonyms: Ubiquitin-like protein ATG12|Autophagy-related protein 12 (APG12-like)|ATG12|APG12|APG12L

    Background: Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus.

    分子量

    48-50 kDa

    基因ID

    9140

    UniProt

    O94817

    途径

    Autophagy
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