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ATG12 抗体

This anti-ATG12 antibody is a 兔 多克隆 antibody detecting ATG12 in WB, ELISA, IHC 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN7111887
发货至: 中国

Quick Overview for ATG12 抗体 (ABIN7111887)

抗原

See all ATG12 抗体
ATG12 (Autophagy Related 12 (ATG12))

适用

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人, 小鼠

宿主

  • 70
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克隆类型

  • 67
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多克隆

标记

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This ATG12 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    ATG12 autophagy related 12 homolog(S. cerevisiae)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:500-1:2000 , IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    ATG12 (Autophagy Related 12 (ATG12))

    别名

    ATG12

    背景

    Synonyms:APG12, APG12L Background:Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus.

    分子量

    48-50kd

    基因ID

    9140

    UniProt

    O94817

    途径

    Autophagy
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