Aryl Hydrocarbon Receptor 抗体
Quick Overview for Aryl Hydrocarbon Receptor 抗体 (ABIN7111734)
抗原
See all Aryl Hydrocarbon Receptor (AHR) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- aryl hydrocarbon receptor
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亚型
- IgG
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应用备注
- WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- Aryl Hydrocarbon Receptor (AHR)
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别名
- AHR
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背景
- Synonyms:Ah receptor, AHR, aryl hydrocarbon receptor, bHLHe76 Background:Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
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分子量
- 105 kDa
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基因ID
- 196
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UniProt
- P35869
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途径
- Regulation of Cell Size
抗原
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