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alpha Actinin 抗体

This anti-alpha Actinin antibody is a 兔 多克隆 antibody detecting alpha Actinin in WB, IHC 和 ELISA. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7111505
发货至: 中国

Quick Overview for alpha Actinin 抗体 (ABIN7111505)

抗原

See all alpha Actinin (ACTN) 抗体
alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))

适用

人, 小鼠, 大鼠, 猴

宿主

  • 9
  • 2

克隆类型

  • 9
  • 2
多克隆

标记

  • 7
  • 2
  • 2
This alpha Actinin antibody is un-conjugated

应用范围

  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    actinin, alpha 1

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))

    别名

    alpha Actinin

    背景

    Synonyms:actinin, alpha 1, ACTN1, alpha Actinin, Alpha actinin 1, F actin cross linking protein, Non muscle alpha actinin 1 Background:Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

    分子量

    110 kDa

    基因ID

    87

    UniProt

    P12814

    途径

    Cell-Cell Junction Organization, Negative Regulation of Transporter Activity
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