ACTN1 抗体 (AA 272-490)
Quick Overview for ACTN1 抗体 (AA 272-490) (ABIN7111505)
抗原
See all ACTN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 272-490
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原理
- ACTN1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 272-490aa
Immunogen: actinin, alpha 1
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ACTN1 (Actinin, alpha 1 (ACTN1))
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别名
- ACTN1
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背景
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Synonyms: Alpha-actinin-1|Alpha-actinin cytoskeletal isoform|F-actin cross-linking protein|Non-muscle alpha-actinin-1|ACTN1
Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
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分子量
- 110 kDa
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基因ID
- 87
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UniProt
- P12814
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途径
- Cell-Cell Junction Organization
抗原
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