AKR1C2 抗体
Quick Overview for AKR1C2 抗体 (ABIN7111467)
抗原
See all AKR1C2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- AKR1C2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- Aldo-keto reductase family 1 member C2
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IF: 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
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别名
- AKR1C2
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背景
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Synonyms: Aldo-keto reductase family 1 member C2|3-alpha-HSD3|Chlordecone reductase homolog HAKRD|Dihydrodiol dehydrogenase 2 (DD-2, DD2)|Dihydrodiol dehydrogenase/bile acid-binding protein (DD/BABP)|Type III 3-alpha-hydroxysteroid dehydrogenase|AKR1C2|DDH2
Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
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分子量
- 37 kDa
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UniProt
- P52895
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途径
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
抗原
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