AKR1C4 抗体
Quick Overview for AKR1C4 抗体 (ABIN7111464)
抗原
See all AKR1C4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- AKR1C4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- aldo-keto reductase family 1, member C4(chlordecone reductase, 3-alpha hydroxysteroid dehydrogenase, type I, dihydrodiol dehydrogenase 4)
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亚型
- IgG
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应用备注
- WB: 1:1000-1:10000, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
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别名
- AKR1C4
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背景
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Synonyms: Aldo-keto reductase family 1 member C4|3-alpha-hydroxysteroid dehydrogenase type I (3-alpha-HSD1)|3alpha-hydroxysteroid 3-dehydrogenase|Chlordecone reductase (CDR)|Dihydrodiol dehydrogenase 4 (DD-4, DD4)|HAKRA|AKR1C4|CHDR
Background: Catalyzes the transformation of the potent androgen dihydrotestosterone(DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol(3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone(kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
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分子量
- 37 kDa
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基因ID
- 1109
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UniProt
- P17516
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途径
- Steroid Hormone Biosynthesis
抗原
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