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ARF1 抗体

The 兔 多克隆 anti-ARF1 antibody (ABIN7111365) specifically detects ARF1 in WB, IHC, ELISA, IF 和 IP. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7111365
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ARF1 抗体 (ABIN7111365)

抗原

See all ARF1 抗体
ARF1 (ADP-Ribosylation Factor 1 (ARF1))

适用

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人, 小鼠

宿主

  • 79
  • 33
  • 1

克隆类型

  • 59
  • 54
多克隆

标记

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This ARF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
  • 原理

    ARF1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: peptide

    Immunogen: ADP-ribosylation factor 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    ARF1 (ADP-Ribosylation Factor 1 (ARF1))

    别名

    ARF1

    背景

    Synonyms: ADP-ribosylation factor 1|ARF1

    Background: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity, the function is linked to AMPA receptor(AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression(LTD).

    分子量

    21 kDa

    基因ID

    375

    UniProt

    P84077

    途径

    Transition Metal Ion Homeostasis, Inositol Metabolic Process
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