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ADCY6 抗体

This anti-ADCY6 antibody is a 兔 多克隆 antibody detecting ADCY6 in WB, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7111340
发货至: 中国

Quick Overview for ADCY6 抗体 (ABIN7111340)

抗原

See all ADCY6 抗体
ADCY6 (Adenylate Cyclase 6 (ADCY6))

适用

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人, 小鼠, 大鼠

宿主

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  • 1

克隆类型

  • 41
  • 2
多克隆

标记

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This ADCY6 antibody is un-conjugated

应用范围

  • 38
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  • 9
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Western Blotting (WB), ELISA, Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    adenylate cyclase 6

    亚型

    IgG
  • 应用备注

    WB: 1:200-1:2000, IP: 1:200-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    ADCY6 (Adenylate Cyclase 6 (ADCY6))

    别名

    ADCY6

    背景

    Synonyms:AC6, ADCY6, adenylate cyclase 6, Adenylate cyclase type 6, Adenylate cyclase type VI, Adenylyl cyclase 6, ATP pyrophosphate lyase 6, DKFZp779F075, KIAA0422 Background:Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors(PubMed:17916776, PubMed:17110384). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells(PubMed:17916776). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion(By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA. This promotes increased phosphorylation of various proteins, including AKT. Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility. May contribute to normal heart function(By similarity). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol(PubMed:17916776). Contributes to bone cell responses to mechanical stimuli(By similarity).

    分子量

    131 kDa

    基因ID

    112

    UniProt

    O43306

    途径

    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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