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ADCY6 抗体 (Internal Region)

The 兔 多克隆 anti-ADCY6 antibody is suitable to detect ADCY6 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA, ICC 和 IF.
产品编号 ABIN6257031
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ADCY6 抗体 (Internal Region) (ABIN6257031)

抗原

See all ADCY6 抗体
ADCY6 (Adenylate Cyclase 6 (ADCY6))

适用

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人, 小鼠, 大鼠

宿主

  • 40
  • 1
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克隆类型

  • 40
  • 1
多克隆

标记

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This ADCY6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 5
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    • 1
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    Internal Region

    特异性

    ADCY5/6 Antibody detects endogenous levels of total ADCY5/6.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human ADCY5/6, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    ADCY6 (Adenylate Cyclase 6 (ADCY6))

    别名

    ADCY5,ADCY6

    背景

    Description: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642, PubMed:26206488, PubMed:24700542). Mediates signaling downstream of ADRB1 (PubMed:24700542). Regulates the increase of free cytosolic Ca2+ in response to increased blood glucose levels and contributes to the regulation of Ca2+-dependent insulin secretion (PubMed:24740569).

    Gene: ADCY5

    分子量

    138 kDa

    基因ID

    111, 112

    UniProt

    O95622, O43306

    途径

    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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