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ATF6 抗体

This 兔 多克隆 antibody specifically detects ATF6 in WB, IHC, ELISA, IP 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7111246
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ATF6 抗体 (ABIN7111246)

抗原

See all ATF6 抗体
ATF6 (Activating Transcription Factor 6 (ATF6))

适用

  • 105
  • 46
  • 36
  • 6
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 96
  • 11
  • 1

克隆类型

  • 86
  • 22
多克隆

标记

  • 54
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This ATF6 antibody is un-conjugated

应用范围

  • 91
  • 31
  • 30
  • 27
  • 27
  • 18
  • 17
  • 16
  • 11
  • 8
  • 7
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)
  • 原理

    ATF6 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    activating transcription factor 6

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    ATF6 (Activating Transcription Factor 6 (ATF6))

    别名

    ATF6

    背景

    Synonyms: Cyclic AMP-dependent transcription factor ATF-6 alpha (cAMP-dependent transcription factor ATF-6 alpha)|Activating transcription factor 6 alpha (ATF6-alpha)|Processed cyclic AMP-dependent transcription factor ATF-6 alpha|ATF6

    Background: Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response(UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element(ERSE)(5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II(5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.

    分子量

    90 kDa

    基因ID

    22926

    UniProt

    P18850

    途径

    ER-Nucleus Signaling, Unfolded Protein Response
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