ACO2 抗体 (AA 51-246)
Quick Overview for ACO2 抗体 (AA 51-246) (ABIN7111197)
抗原
See all ACO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-246
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原理
- ACO2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 51-246aa
Immunogen: aconitase 2, mitochondrial
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ACO2 (Aconitase 2, Mitochondrial (ACO2))
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别名
- ACO2
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背景
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Synonyms: Aconitate hydratase, mitochondrial (Aconitase)|Citrate hydro-lyase|ACO2
Background: ACO2(aconitate hydratase, mitochondrial) is also named as citrate hydro-lyase and belongs to the aconitase/IPM isomerase family. It plays a key function in cellular energy production, and loss of its activity has a major impact on cellular and organismal survival. Western blot shows two bands of 83 kDa and 40 kDa. The 40 kDa fragment decreases with age and oxidative stress, whereas other fragmentation products with molecular weights between 40 and 83 kDa increased with age and MnSOD(mitochondrial manganese superoxide dismutase) deficiency(PMID:12459471). Defects in ACO2 are the cause of infantile cerebellar-retinal degeneration(ICRD).
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分子量
- 85 kDa
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基因ID
- 50
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UniProt
- Q99798
抗原
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