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ACO2 抗体 (AA 51-246)

This anti-ACO2 antibody is a 兔 多克隆 antibody detecting ACO2 in WB, ELISA, IHC 和 IF. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7111197
发货至: 中国

Quick Overview for ACO2 抗体 (AA 51-246) (ABIN7111197)

抗原

See all ACO2 抗体
ACO2 (Aconitase 2, Mitochondrial (ACO2))

适用

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  • 38
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  • 2
  • 2
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人, 大鼠, 小鼠

宿主

  • 54
  • 6
  • 4

克隆类型

  • 47
  • 17
多克隆

标记

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This ACO2 antibody is un-conjugated

应用范围

  • 43
  • 26
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  • 8
  • 6
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-246

    原理

    ACO2 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 51-246aa

    Immunogen: aconitase 2, mitochondrial

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    ACO2 (Aconitase 2, Mitochondrial (ACO2))

    别名

    ACO2

    背景

    Synonyms: Aconitate hydratase, mitochondrial (Aconitase)|Citrate hydro-lyase|ACO2

    Background: ACO2(aconitate hydratase, mitochondrial) is also named as citrate hydro-lyase and belongs to the aconitase/IPM isomerase family. It plays a key function in cellular energy production, and loss of its activity has a major impact on cellular and organismal survival. Western blot shows two bands of 83 kDa and 40 kDa. The 40 kDa fragment decreases with age and oxidative stress, whereas other fragmentation products with molecular weights between 40 and 83 kDa increased with age and MnSOD(mitochondrial manganese superoxide dismutase) deficiency(PMID:12459471). Defects in ACO2 are the cause of infantile cerebellar-retinal degeneration(ICRD).

    分子量

    85 kDa

    基因ID

    50

    UniProt

    Q99798
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