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ABHD2 抗体

This anti-ABHD2 antibody is a 兔 多克隆 antibody detecting ABHD2 in ELISA, WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7111166
发货至: 中国

Quick Overview for ABHD2 抗体 (ABIN7111166)

抗原

See all ABHD2 抗体
ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))

适用

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人, 小鼠, 大鼠

宿主

  • 33

克隆类型

  • 33
多克隆

标记

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  • 1
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This ABHD2 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    ABHD2 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    abhydrolase domain containing 2

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))

    别名

    ABHD2

    背景

    Synonyms: Monoacylglycerol lipase ABHD2|2-arachidonoylglycerol hydrolase|Abhydrolase domain-containing protein 2|Acetylesterase|Lung alpha/beta hydrolase 2|Progesterone-sensitive lipase|Protein PHPS1-2|ABHD2|LABH2

    Background: Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol(AG) from cell membrane(PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol(1AG) and 2-arachidonoylglycerol(2AG) to glycerol and arachidonic acid(AA)(PubMed:26989199). Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation(PubMed:26989199). May also play a role in smooth muscle cells migration(By similarity).

    分子量

    48 kDa

    基因ID

    11057

    UniProt

    P08910
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