XRN2 抗体
Quick Overview for XRN2 抗体 (ABIN7111135)
抗原
See all XRN2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- XRN2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- 5'-3' exoribonuclease 2
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亚型
- IgG
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应用备注
- WB: 1:200-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- XRN2 (5'-3' Exoribonuclease 2 (XRN2))
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别名
- XRN2
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背景
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Synonyms: 5'-3' exoribonuclease 2|DHM1-like protein (DHP protein)|XRN2
Background: Possesses 5'->3' exoribonuclease activity(By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II(RNAp II) transcription termination R-loops formed by G-rich pause sites(PubMed:21700224).
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分子量
- 108 kDa
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基因ID
- 22803
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UniProt
- Q9H0D6
抗原
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