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Mesothelin 抗体 (AA 296-580) (Biotin)

The Biotin-conjugated 兔 单克隆 anti-Mesothelin antibody (Clone DM71) (ABIN7093016) specifically detects Mesothelin in ELISA 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7093016
发货至: 中国
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Quick Overview for Mesothelin 抗体 (AA 296-580) (Biotin) (ABIN7093016)

抗原

See all Mesothelin (MSLN) 抗体
Mesothelin (MSLN)

适用

  • 176
  • 52
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  • 1
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宿主

  • 119
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  • 1
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克隆类型

  • 116
  • 86
  • 3
单克隆

标记

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This Mesothelin antibody is conjugated to Biotin

应用范围

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ELISA, Flow Cytometry (FACS)

克隆位点

DM71
  • 抗原表位

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    AA 296-580

    原理

    Biotinylated Anti-mesothelin antibody(DM71), Rabbit mAb

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    免疫原

    Recombinant human mesothelin (Glu296-Gly580) (ABIN6961104) produced by using human HEK293 cells

    亚型

    IgG
  • 应用备注

    ELISA 1:5000-10000, Flow Cyt 1:100

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please see Certificate of Analysis for specific instructions of reconstitution.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    Mesothelin (MSLN)

    别名

    MSLN

    背景

    Synonyms:MSLN, Mesothelin, MPF
    Description:This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

    分子量

    68.9kDa

    基因ID

    10232

    UniProt

    Q13421

    途径

    EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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