CD276 抗体 (AA 29-245) (Biotin)
Quick Overview for CD276 抗体 (AA 29-245) (Biotin) (ABIN7093001)
抗原
See all CD276 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - AA 29-245
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纯化方法
 - Purified from cell culture supernatant by affinity chromatography
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免疫原
 - Recombinant human B7H3(Leu29-Pro245) (ABIN6961085) produced by using human HEK293 cells
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亚型
 - IgG
 
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应用备注
 - ELISA 1/5000-10000,Flow Cyt 1/100
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限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Reconstitute with deionized water
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缓冲液
 - 50 % Glycerol, PBS, pH 7.4, 0.1 % BSA,0.1 % Procline 300
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C,-80 °C
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储存方法
 - Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
 - 12 months
 
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- CD276
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别名
 - B7-H3
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背景
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                        Synonyms:B7-H3, CD276, B7 homolog 3, B7H3
Description:The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. - 
                                            
分子量
 - 57 kDa
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基因ID
 - 80381
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UniProt
 - Q5ZPR3
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途径
 - Cancer Immune Checkpoints
 
抗原
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