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RAD21 抗体 (AA 531-631) (Biotin)

This anti-RAD21 antibody is a 兔 多克隆 antibody detecting RAD21 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人 和 大鼠.
产品编号 ABIN706393
发货至: 中国

Quick Overview for RAD21 抗体 (AA 531-631) (Biotin) (ABIN706393)

抗原

See all RAD21 抗体
RAD21 (RAD21 Homolog (RAD21))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This RAD21 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 531-631

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Rad2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    RAD21 (RAD21 Homolog (RAD21))

    别名

    RAD21

    背景

    Synonyms: HR21, MCD1, NXP1, SCC1, CDLS4, hHR21, HRAD21, Double-strand-break repair protein rad21 homolog, Nuclear matrix protein 1, NXP-1, SCC1 homolog, RAD21, KIAA0078

    Background: Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.

    基因ID

    5885

    UniProt

    O60216

    途径

    Positive Regulation of Endopeptidase Activity
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