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CD46 抗体 (AA 35-328)

This 兔 单克隆 anti-CD46 antibody (Clone DM145) specifically detects CD46 in FACS 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7092945
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for CD46 抗体 (AA 35-328) (ABIN7092945)

抗原

See all CD46 抗体
CD46

适用

  • 141
  • 34
  • 20
  • 11
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  • 3

宿主

  • 90
  • 68
  • 2
  • 2

克隆类型

  • 93
  • 69
单克隆

标记

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  • 1
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This CD46 antibody is un-conjugated

应用范围

  • 94
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  • 35
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  • 9
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  • 5
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Flow Cytometry (FACS), ELISA

克隆位点

DM145
  • 抗原表位

    • 16
    • 10
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    • 3
    • 2
    • 2
    • 2
    • 2
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    • 1
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    AA 35-328

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    免疫原

    Recombinant human CD46(Cys35-Asp328) (ABIN6964079) produced by using human HEK293 cells

    亚型

    IgG
  • 应用备注

    ELISA 1/5000-10000,Flow Cyt 1/100

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute with deionized water

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    CD46

    别名

    CD46

    背景

    Synonyms:CD46,AHUS2,MCP,MIC10,TLX,TRA2.10
    Description:The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

    分子量

    43.7KDa

    途径

    Regulation of Actin Filament Polymerization
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