CD46 抗体 (AA 35-328)
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- 抗原 See all CD46 抗体
- CD46
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抗原表位
- AA 35-328
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This CD46 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), ELISA
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 免疫原
- Recombinant human CD46(Cys35-Asp328) (ABIN6964079) produced by using human HEK293 cells
- 克隆位点
- DM145
- 亚型
- IgG
- Top Product
- Discover our top product CD46 Primary Antibody
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- 应用备注
- ELISA 1/5000-10000,Flow Cyt 1/100
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CD46
- 别名
- CD46 (CD46 产品)
- 背景
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Synonyms:CD46,AHUS2,MCP,MIC10,TLX,TRA2.10
Description:The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. - 分子量
- 43.7KDa
- 途径
- Regulation of Actin Filament Polymerization
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