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PD-L1 抗体 (AA 19-328)

PD-L1 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM123 unconjugated
产品编号 ABIN7092924
发货至: 中国
  • 抗原 See all PD-L1 抗体
    PD-L1 (CD274 (PD-L1))
    抗原表位
    • 29
    • 16
    • 15
    • 12
    • 11
    • 9
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 19-328
    适用
    • 160
    • 105
    • 63
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    宿主
    • 124
    • 55
    • 15
    • 4
    • 2
    • 1
    克隆类型
    • 108
    • 91
    • 2
    单克隆
    标记
    • 90
    • 13
    • 13
    • 11
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    This PD-L1 antibody is un-conjugated
    应用范围
    • 135
    • 98
    • 55
    • 40
    • 37
    • 28
    • 16
    • 16
    • 14
    • 14
    • 10
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), ELISA
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    免疫原
    Recombinant human PD-L1 (Phe19-Arg328) (ABIN6961165) produced by using human HEK293 cells
    克隆位点
    DM123
    亚型
    IgG
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • 应用备注
    ELISA 1/5000-10000,Flow Cyt  1/100
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    PD-L1 (CD274 (PD-L1))
    别名
    PD-L1 (PD-L1 产品)
    别名
    B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
    背景
    Synonyms:PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1
    Description:This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
    分子量
    26 kDa
    基因ID
    29126
    UniProt
    Q9NZQ7
    途径
    Cancer Immune Checkpoints
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