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PD-L1 抗体 (AA 19-328)

This 兔单克隆 antibody specifically detects PD-L1 in FACS 和 ELISA. It exhibits reactivity toward 人.

Flow cytometry analysis with Anti-PD-L1 (DM123) on Expi293 cells transfected with human PD-L1 (Blue histogram) or Expi293 transfected with irrelevant protein(Red histogram). (PD-L1 抗体 (AA 19-328))

FACS

ELISA

2 images

产品编号 ABIN7092924

发货至: 中国

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Quick Overview for PD-L1 抗体 (AA 19-328) (ABIN7092924)

抗原

See all PD-L1 抗体

PD-L1 (CD274 (PD-L1))

适用

人

宿主

兔

克隆类型

单克隆

标记

This PD-L1 antibody is un-conjugated

应用范围

Flow Cytometry (FACS), ELISA

克隆位点

DM123

Discover our top product PD-L1 Primary Antibody

抗原表位
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1
AA 19-328

纯化方法

Purified from cell culture supernatant by affinity chromatography

免疫原

Recombinant human PD-L1 (Phe19-Arg328) (ABIN6961165) produced by using human HEK293 cells

亚型

IgG
anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 适用: 人 WB, FACS, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 9B5F4 unconjugated

anti-CD274 (PD-L1) (AA 39-191) antibody
PD-L1 适用: 人, 小鼠 WB, FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal PDL1-2746 unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 6D9A2 unconjugated

anti-CD274 (PD-L1) (AA 48-290) antibody
PD-L1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 34-241) antibody
PD-L1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
KO Validated PD-L1 适用: 人 WB, FACS, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 7D2A10 unconjugated

anti-CD274 (PD-L1) (AA 24-234) antibody
PD-L1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) antibody
PD-L1 适用: 人 IHC 宿主: 兔 Monoclonal 711R unconjugated Recombinant Antibody

应用备注

ELISA 1/5000-10000,Flow Cyt 1/100

限制

仅限研究用
状态

Lyophilized

溶解方式

Reconstitute with deionized water

缓冲液

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

有效期

12 months
抗原

PD-L1 (CD274 (PD-L1))

别名

PD-L1

背景

Synonyms:PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1
Description:This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.

分子量

26 kDa

基因ID

29126

UniProt

Q9NZQ7

途径

Cancer Immune Checkpoints