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VCP 抗体

This anti-VCP antibody is a 小鼠 单克隆 antibody detecting VCP in WB, IF, IHC (p), ICC 和 IHC (fro). Suitable for 人.
产品编号 ABIN7091810
发货至: 中国

Quick Overview for VCP 抗体 (ABIN7091810)

抗原

See all VCP 抗体
VCP (Valosin Containing Protein (VCP))

适用

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宿主

  • 77
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  • 2
小鼠

克隆类型

  • 68
  • 29
单克隆

标记

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This VCP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

N5A9
  • 预测反应

    Human,Mouse

    免疫原

    Recombinant human VCP.
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF()
    ICC 1:100-500

    限制

    仅限研究用
  • 浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    VCP (Valosin Containing Protein (VCP))

    别名

    VCP

    背景

    Synonyms: valosin-containing protein, 15S Mg(2+) ATPase p97 subunit, ATPase p97, IBMPFD, MGC131997, MGC148092, MGC8560, p97, TER ATPase, TERA, transitional endoplasmic reticulum ATPase, valosin-containing protein, yeast Cdc48p homolog, Transitional endoplasmic reticulum ATPase, TER ATPase, 15S Mg(2+)-ATPase p97 subunit, p97, TERA_HUMAN.

    Background: Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity). Regulates E3 ubiquitin-protein ligase activity of RNF19A.

    基因ID

    7415

    UniProt

    P55072

    途径

    ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway
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