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TSC1 抗体

This anti-TSC1 antibody is a 小鼠 单克隆 antibody detecting TSC1 in WB. Suitable for 人.
产品编号 ABIN7091774
发货至: 中国

Quick Overview for TSC1 抗体 (ABIN7091774)

抗原

See all TSC1 抗体
TSC1 (Tuberous Sclerosis 1 (TSC1))

适用

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宿主

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小鼠

克隆类型

  • 306
  • 16
单克隆

标记

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This TSC1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

K6F13
  • 预测反应

    Human

    免疫原

    Recombinant human TSC1 (Fragment) (His-tagged).

    亚型

    IgG2b
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    TSC1 (Tuberous Sclerosis 1 (TSC1))

    别名

    TSC1

    背景

    Synonyms: LAM, Hamartin, Tuberous sclerosis 1 protein, TSC1_HUMAN, KIAA0243, TSC, Tuberous sclerosis 1.

    Background: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

    基因ID

    7248

    UniProt

    Q92574

    途径

    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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