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SP1 抗体

The 小鼠 单克隆 anti-SP1 antibody is suitable to detect SP1 in samples from 人. It has been validated for WB, IF 和 ICC.
产品编号 ABIN7091692
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SP1 抗体 (ABIN7091692)

抗原

See all SP1 抗体
SP1 (Sp1 Transcription Factor (SP1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

Y5R2
  • 预测反应

    Human

    免疫原

    Recombinant human SP1.
  • 应用备注

    WB 1:300-5000
    IF()
    ICC 1:100-500

    限制

    仅限研究用
  • 浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    SP1 (Sp1 Transcription Factor (SP1))

    别名

    SP1

    背景

    Synonyms: Sp1 transcription factor isoform a, TSFP1, TSFP 1, Specificity protein 1, Transcription factor Sp1, SP1_HUMAN.

    Background: Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression.

    基因ID

    6667

    UniProt

    P08047

    途径

    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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