RPSA/Laminin Receptor 抗体
Quick Overview for RPSA/Laminin Receptor 抗体 (ABIN7091650)
抗原
See all RPSA/Laminin Receptor (RPSA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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预测反应
- Mouse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RPSA
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF()
ICC 1:100-500 -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
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别名
- RPSA
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背景
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Synonyms: 67 kDa Laminin Receptor, 37LRP, P37- kDa laminin receptor precursor, MGr1-Ag, laminin receptor 1, 67kD, ribosomal protein SA, 34/67 kDa laminin receptor, 40S ribosomal protein SA, 67LR, Colon carcinoma laminin-binding protein, LAMBR, Laminin Receptor 1, LAMR 1, LAMR1, LRP, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, p40, Ribosomal Protein SA, 67kD laminin receptor, Laminin Receptor 1, Laminin R1, LNR1, RSSA_HUMAN.
Background: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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基因ID
- 3921
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UniProt
- P08865
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途径
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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