Nanog 抗体
Quick Overview for Nanog 抗体 (ABIN7091450)
抗原
See all Nanog (NANOG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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预测反应
- Human
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免疫原
- Recombinant human NANOG.
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Nanog (NANOG) (Nanog Homeobox (NANOG))
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别名
- NANOG
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背景
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Synonyms: NANOG_MOUSE, Embryonic stem cell specific homeobox protein (Nanog), ENK, FLJ12581, FLJ40451, Homeobox transcription factor Nanog, Nanog homeobox, Homeobox protein NANOG, ES cell-associated protein 4, Early embryo specific expression NK-type homeobox protein, Homeobox transcription factor Nanog, Nanog, Ecat4.
Background: Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, promotes cells to enter into S phase and proliferation.
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基因ID
- 79923
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UniProt
- Q80Z64
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途径
- Stem Cell Maintenance
抗原
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