MME 抗体 (AA 401-550)
Quick Overview for MME 抗体 (AA 401-550) (ABIN7091386)
抗原
See all MME 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 401-550
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预测反应
- Human
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免疫原
- KLH conjugated synthetic peptide derived from human CD10
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- MME (Membrane Metallo-Endopeptidase (MME))
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别名
- CD10
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背景
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Synonyms: MME, NEP, NEP_HUMAN, Atriopeptidase, CALLA, CD 10, CD10, Common acute lymphocytic leukemia antigen, DKFZp686O16152, EC 3.4.24.11, Enkephalinase, EPN, gp100, Membrane metallo endopeptidase, Membrane metalloendopeptidase, Membrane metalloendopeptidase neutral endopeptidase enkephalinase, Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10, Membrane metalloendopeptidase variant 1, Membrane metalloendopeptidase variant 2, MGC126681, MGC126707, Neprilysin, Neutral endopeptidase 24.11, Neutral endopeptidase, Neprilysin, Skin fibroblast elastase, SFE.
Background: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
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基因ID
- 4311
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UniProt
- P08473
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途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
抗原
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