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IDO1 抗体

This anti-IDO1 antibody is a 兔 单克隆 antibody detecting IDO1 in IHC (p). Suitable for 人.
产品编号 ABIN7091242
发货至: 中国

Quick Overview for IDO1 抗体 (ABIN7091242)

抗原

See all IDO1 抗体
IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

适用

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宿主

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克隆类型

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单克隆

标记

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This IDO1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

ID2C1
  • 交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human IDO1

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

    别名

    IDO1

    背景

    Synonyms: Indoleamine 2, 3-dioxygenase , 3-dioxygenase, I23O1_HUMAN, IDO 1, IDO, IDO-1, INDO, indolamine 2,3 dioxygenase, Indole 2 3 dioxygenase, indoleamine 2 3 dioxygenase 1, indoleamine 2 3 dioxygenase, Indoleamine 2,3-dioxygenase 1, Indoleamine pyrrole 2 3 dioxygenase, Indoleamine-pyrrole 2, indoleamine-pyrrole 2,3 dioxygenase.

    Background: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]

    基因ID

    3620

    UniProt

    P14902

    途径

    Activated T Cell Proliferation
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