HMGB1 抗体 (AA 100-200)
Quick Overview for HMGB1 抗体 (AA 100-200) (ABIN7091206)
抗原
See all HMGB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-200
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特异性
- KO-Validated
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HMGB1
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF() -
限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- HMGB1 (High Mobility Group Box 1 (HMGB1))
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别名
- HMGB1
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背景
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Synonyms: Amphoterin, High mobility group 1, High Mobility Group Box 1, High mobility group protein 1, High mobility group protein B1, HMG3, HMGB 1,HMGB-1, Hmgb1 protein, Nonhistone chromosomal protein HMG1, SBP 1, SBP-1, Sulfoglucuronyl carbohydrate binding protein, HMGB1_HUMAN.
Background: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.
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基因ID
- 3146
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UniProt
- P09429
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途径
- p53 Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
抗原
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