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FGFR2 抗体

The 兔 单克隆 anti-FGFR2 antibody is suitable to detect FGFR2 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7091110
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FGFR2 抗体 (ABIN7091110)

抗原

See all FGFR2 抗体
FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

适用

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宿主

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克隆类型

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单克隆

标记

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This FGFR2 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

E2F12
  • 预测反应

    Human,Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FGFR2

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

    别名

    FGFR2

    背景

    Synonyms: KGFR, KSAM, Bacteria expressed kinase, BEK, BEK fibroblast growth factor receptor, BFR 1, BFR1, CD 332, CD332, CD332 antigen, CEK 3, CEK3, CFD 1, CFD1, Craniofacial dysostosis 1, Crouzon syndrome, ECT 1, ECT 1, ECT1, FGF receptor, FGFR 2, FGFR-2, FGFR2_HUMAN, Fibroblast growth factor receptor 2, Hydroxyaryl protein kinase, Hydroxyaryl protein kinase, Jackson Weiss syndrome, JWS, JWS antibody K SAM, K sam protein, K sam protein, K-sam , Keratinocyte growth factor receptor 2, Keratinocyte growth factor receptor, Pfeiffer syndrome, Protein tyrosine kinase receptor like 14, TK14, TK25, Tyrosylprotein kinase, Tyrosylprotein kinase.

    Background: The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]

    基因ID

    2263

    UniProt

    P21802

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
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