EPH Receptor B4 抗体
Quick Overview for EPH Receptor B4 抗体 (ABIN7091064)
抗原
See all EPH Receptor B4 (EPHB4) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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预测反应
- Human
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免疫原
- Recombinant human EPHB4.
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- EPH Receptor B4 (EPHB4)
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别名
- EPHB4
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背景
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Synonyms: Eph receptor B4, EPHB4_HUMAN, Ephrin type-B receptor 4, Hepatoma Transmembrane Kinase, HTK, MYK1, TYRO11, Tyrosine-protein kinase receptor HTK, Tyrosine-protein kinase TYRO11.
Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.
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基因ID
- 2050
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UniProt
- P54760
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途径
- RTK signaling
抗原
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