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DKK2 抗体

DKK2 适用: 人 WB 宿主: 小鼠 Monoclonal J3F5 unconjugated
产品编号 ABIN7091038
发货至: 中国
  • 抗原 See all DKK2 抗体
    DKK2 (Dickkopf 2 Homolog (DKK2))
    适用
    • 51
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 47
    • 3
    • 1
    小鼠
    克隆类型
    • 48
    • 3
    单克隆
    标记
    • 27
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DKK2 antibody is un-conjugated
    应用范围
    • 39
    • 26
    • 24
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    预测反应
    Human,Mouse
    免疫原
    Recombinant human DKK2.
    克隆位点
    J3F5
    Top Product
    Discover our top product DKK2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    限制
    仅限研究用
  • 浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    DKK2 (Dickkopf 2 Homolog (DKK2))
    别名
    DKK2 (DKK2 产品)
    背景

    Synonyms: Dickkopf 2, Dickkopf gene 2, Dickkopf homolog 2, Dickkopf related protein 2, Dickkopf-2, Dickkopf-related protein 2, Dickkopf2, DKK 2, Dkk-2, DKK2_HUMAN, hDkk 2, hDkk-2, hDkk2.

    Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

    基因ID
    27123
    UniProt
    Q9UBU2
    途径
    WNT signaling
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