F2RL3 抗体 (AA 101-200)
Quick Overview for F2RL3 抗体 (AA 101-200) (ABIN7090992)
抗原
See all F2RL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-200
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Cow,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PAWR
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000 -
限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
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别名
- Par-4
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背景
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Synonyms: 2310001G03Rik , PAR 4 , PAR-4 , Pawr , PAWR_HUMAN , PRKC Apoptosis WT1 Regulator , PRKC apoptosis WT1 regulator protein , Prostate apoptosis response 4 protein , Prostate apoptosis response protein 4 , prostate apoptosis response protein PAR-4 , Transcriptional repressor Par-4-like protein PAWR , Transcriptional repressor PAR4 , WT1 Interacting Protein
Background: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.
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基因ID
- 5074
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UniProt
- Q96IZ0
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途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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