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CD276 抗体

This anti-CD276 antibody is a 小鼠 单克隆 antibody detecting CD276 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN7090884
发货至: 中国

Quick Overview for CD276 抗体 (ABIN7090884)

抗原

See all CD276 抗体
CD276

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD276 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

F6D12
  • 预测反应

    Human

    免疫原

    Recombinant human CD276.
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    CD276

    别名

    CD276

    背景

    Synonyms: B7H3, 4Ig B7 H3, 4Ig-B7-H3, AU016588, B7 H3, B7 homolog 3, B7-H3, B7H3, B7RP-2, CD_antigen=CD276, CD276, CD276 antigen, CD276 Molecule, CD276_HUMAN, Costimulatory molecule, PSEC0249, UNQ309/PRO352.

    Background: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

    基因ID

    80381

    UniProt

    Q5ZPR3

    途径

    Cancer Immune Checkpoints
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