CD276 抗体
Quick Overview for CD276 抗体 (ABIN7090884)
抗原
See all CD276 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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预测反应
 - Human
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免疫原
 - Recombinant human CD276.
 
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应用备注
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                        WB 1:300-5000
IHC-P 1:200-400 - 
                                            
限制
 - 仅限研究用
 
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浓度
 - 0.5 μg/μL
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缓冲液
 - 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
 - 12 months
 
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- CD276
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别名
 - CD276
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背景
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Synonyms: B7H3, 4Ig B7 H3, 4Ig-B7-H3, AU016588, B7 H3, B7 homolog 3, B7-H3, B7H3, B7RP-2, CD_antigen=CD276, CD276, CD276 antigen, CD276 Molecule, CD276_HUMAN, Costimulatory molecule, PSEC0249, UNQ309/PRO352.
Background: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
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基因ID
 - 80381
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UniProt
 - Q5ZPR3
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途径
 - Cancer Immune Checkpoints
 
抗原
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