UGT2B4 抗体 (AA 111-210) (Cy5)
Quick Overview for UGT2B4 抗体 (AA 111-210) (Cy5) (ABIN705510)
抗原
See all UGT2B4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 111-210
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预测反应
- Human,Sheep
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human UGT2B4
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))
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别名
- UGT2B4
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背景
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Synonyms: HLUG25, Hyodeoxycholic acid, UDP glucuronosyltransferase 2 family polypeptide B4, UDP glucuronosyltransferase 2B4 precursor, UDP glucuronyltransferase family 2 beta 4, UDP glycosyltransferase 2 family polypeptide B4, UDP glycosyltransferase, UDPGT, UDPGTh 1, UDPGTh1, UGT2B11, UGT2B4, UD2B4_HUMAN.
Background: The UDP-Glucuronosyltransferases (UGT) comprise a family of enzymes that detoxify and enhance the urinary excretion of a wide variety of xenobiotic and endogenous substrates by transferring glucuronic acid to sulfhydryl, hydroxyl, aromatic amino, or carboxylic acid groups. They have been subdivided into two families, UGT1 and UGT2, based on the evolutionary divergence of their genes. The enzymes of the UGT1A family play an important role in the metabolism of dietary constituents, phenols, and therapeutic drugs, and also the glucuronidation of bilirubin and iodothyronines. The enzymes of the UGT2B family are involved in the metabolism of bile acids, phenol derivatives, catecholestrogens and steroids. Although it is widely recognized that the liver is the major site of glucuronidation, it is now clear that UGT enzymes are also found in extra-hepatic tissues.
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基因ID
- 7363
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途径
- Steroid Hormone Biosynthesis
抗原
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