Cullin 2 抗体 (AA 365-745) (Biotin)
Quick Overview for Cullin 2 抗体 (AA 365-745) (Biotin) (ABIN705268)
抗原
See all Cullin 2 (CUL2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 365-745
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预测反应
- Human,Mouse,Rat,Dog,Cow,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Cullin 2
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亚型
- IgG
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- Cullin 2 (CUL2)
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别名
- Cullin 2
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背景
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Synonyms: Cullin2, Cullin-2, CUL 2, MGC131970, CUL2_HUMAN.
Background: Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
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基因ID
- 8453
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途径
- M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
抗原
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