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Myeloperoxidase 抗体 (FITC)

This anti-Myeloperoxidase antibody is a 小鼠 单克隆 antibody detecting Myeloperoxidase in FACS. Suitable for 人.
产品编号 ABIN7077551
发货至: 中国

Quick Overview for Myeloperoxidase 抗体 (FITC) (ABIN7077551)

抗原

See all Myeloperoxidase (MPO) 抗体
Myeloperoxidase (MPO)

适用

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宿主

  • 147
  • 90
  • 1
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小鼠

克隆类型

  • 134
  • 106
单克隆

标记

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  • 1
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  • 1
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This Myeloperoxidase antibody is conjugated to FITC

应用范围

  • 146
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Flow Cytometry (FACS)

质量等级

GMP Grade

克隆位点

8-9
  • 原理

    MPO FITC Antibody

    产品特性

    The clone 8/9, a mouse monoclonal antibody selectively binds with myeloperoxidase (MPO), a glycoprotein present in the granules of myeloid cells. MPO is critical for an optimal oxygen-dependent microbicidal activity of myeloid cells. The MPO generally appears in the myeloblast stage of myeloid cell differentiation. It is the most common functional protein of myeloid cells and is involved in the process of inflammatory immune responses mediated by myeloid cells. The primary translation product of MPO undergoes glycosylation with the production of 89 kDa heme-free apopro-MPO form followed by incorporation of heme and conversion into the enzymatically active pro-MPO form. Subsequently, pro-MPO becomes targeted to azurophil granules where final processing occurs to produce mature dimeric MPO consisting of the 59-64 kDa MPO alpha-chain and the 14 kDa MPO beta-chain. MPO gene expression may serve as an additional marker for subclassification of acute leukemias and may be used to identify leukemic cells arrested at an early stage of the myeloid differentiation pathway.

    纯化方法

    Purified

    纯度

    >95 %

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C, Conjugated antibodies should never be frozen.
  • 抗原

    Myeloperoxidase (MPO)

    别名

    MPO

    基因ID

    4353

    UniProt

    P05164

    途径

    Chromatin Binding
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