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- 抗原 See all CD276 抗体
- CD276
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD276 antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 产品特性
- The clone DCN.70, a mouse monoclonal antibody selectively binds with a k type I membrane protein commonly known as CD276, a member of B7-H3 immunoregulatory family. It is not expressed by lymphocytes or granulocytes but weakly expressed on resting monocytes. Increased expression is observed on monocytes derived dendritic cells as well as in a variety of cancer types, including breast, pancreatic, and ovarian cancer. CD276 expression has been correlated with poor survival in ovarian cancer subjects. CD276 blockade, especially when combined with an anti-PD-1 blockade, is a promising strategy for the treatment of B7-H3-expressing NSCLCs that arerefractory to anti-PD-1 therapy, making CD276 a promising clinical molecular target.
- 纯化方法
- Purified
- 纯度
- >95 %
- 质量等级
- GMP Grade
- 免疫原
- Human Dendritic Cells
- 克隆位点
- DCN-70
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD276 Primary Antibody
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anti-CD276 (CD276) (AA 29-466) antibody
CD276 适用: 人 WB, ELISA, FACS, IHC, ICC 宿主: 小鼠 Monoclonal 8C1C2 unconjugated
anti-CD276 (CD276) (AA 47-219) antibodyCD276 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 47-213) antibodyCD276 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) antibodyCD276 适用: 人 WB, ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 6A1 unconjugated
anti-CD276 (CD276) (AA 493-522), (C-Term) antibodyCD276 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB31111 unconjugated
anti-CD276 (CD276) (AA 237-358) antibodyCD276 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-CD276 (CD276) (AA 100-200) antibodyCD276 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 101-200) antibodyCD276 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 47-219) antibodyCD276 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-CD276 (CD276) (AA 29-200) antibodyCD276 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS pH 7.2, 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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- 抗原
- CD276
- 别名
- CD276 (CD276 产品)
- 别名
- sc:d0645 antibody, zgc:158279 antibody, 6030411F23Rik antibody, AU016588 antibody, B7RP-2 antibody, B7h3 antibody, B7H3 antibody, 4Ig-B7-H3 antibody, B7-H3 antibody, CD276 molecule antibody, CD276 molecule S homeolog antibody, CD276 antigen antibody, Cd276 molecule antibody, CD276 antibody, cd276.S antibody, cd276 antibody, Cd276 antibody
- 背景
- The clone DCN.70, a mouse monoclonal antibody selectively binds with a k type I membrane protein commonly known as CD276, a member of B7-H3 immunoregulatory family. It is not expressed by lymphocytes or granulocytes but weakly expressed on resting monocytes. Increased expression is observed on monocytes derived dendritic cells as well as in a variety of cancer types, including breast, pancreatic, and ovarian cancer. CD276 expression has been correlated with poor survival in ovarian cancer subjects. CD276 blockade, especially when combined with an anti-PD-1 blockade, is a promising strategy for the treatment of B7-H3-expressing NSCLCs that arerefractory to anti-PD-1 therapy, making CD276 a promising clinical molecular target.
- 基因ID
- 80381
- UniProt
- Q5ZPR3
- 途径
- Cancer Immune Checkpoints
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