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NGFR 抗体 (iFluor™647)

This anti-NGFR antibody is a 小鼠 单克隆 antibody detecting NGFR in FACS. Suitable for 人.
产品编号 ABIN7077081
发货至: 中国

Quick Overview for NGFR 抗体 (iFluor™647) (ABIN7077081)

抗原

See all NGFR 抗体
NGFR (Nerve Growth Factor Receptor (NGFR))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This NGFR antibody is conjugated to iFluor™647

应用范围

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Flow Cytometry (FACS)

质量等级

GMP Grade

克隆位点

ME20-4
  • 原理

    CD271 iFluor647 Antibody

    产品特性

    The clone ME20.4, a mouse monoclonal antibody selectively binds with a ~75 kD type I transmembrane protein known as CD271. It is also known as the nerve growth factor receptor (NGFR) and a member of the tumor necrosis factor receptor (TNFR) superfamily.  Various cell types express CD271 including neuronal axons, Schwann cells, mesenchymal stem cells, epithelial cells, etc.  Increased levels of CD271 were observed in brain metastatic melanoma cells and in lung-metastasizing melanoma cells. It is a transmembrane signaling receptor involved in negative cell cycle regulation and is specific for neural crest origin.

    纯化方法

    Purified

    纯度

    >95 %

    免疫原

    WM245 melanoma cells

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C, Conjugated antibodies should never be frozen.
  • 抗原

    NGFR (Nerve Growth Factor Receptor (NGFR))

    别名

    CD271

    基因ID

    4804

    UniProt

    P08138

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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