NGFR 抗体 (iFluor™647)
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- 抗原 See all NGFR 抗体
- NGFR (Nerve Growth Factor Receptor (NGFR))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NGFR antibody is conjugated to iFluor™647
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应用范围
- Flow Cytometry (FACS)
- 原理
- CD271 iFluor647 Antibody
- 产品特性
- The clone ME20.4, a mouse monoclonal antibody selectively binds with a ~75 kD type I transmembrane protein known as CD271. It is also known as the nerve growth factor receptor (NGFR) and a member of the tumor necrosis factor receptor (TNFR) superfamily. Various cell types express CD271 including neuronal axons, Schwann cells, mesenchymal stem cells, epithelial cells, etc. Increased levels of CD271 were observed in brain metastatic melanoma cells and in lung-metastasizing melanoma cells. It is a transmembrane signaling receptor involved in negative cell cycle regulation and is specific for neural crest origin.
- 纯化方法
- Purified
- 纯度
- >95 %
- 质量等级
- GMP Grade
- 免疫原
- WM245 melanoma cells
- 克隆位点
- ME20-4
- 亚型
- IgG1, kappa
- Top Product
- Discover our top product NGFR Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- 抗原
- NGFR (Nerve Growth Factor Receptor (NGFR))
- 别名
- CD271 (NGFR 产品)
- 基因ID
- 4804
- UniProt
- P08138
- 途径
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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