CD166 抗体 (iFluor™647)
Quick Overview for CD166 抗体 (iFluor™647) (ABIN7076855)
抗原
See all CD166 (ALCAM) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD166 iFluor 647 Antibody
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产品特性
- The clone 3A6, a mouse monoclonal antibody, recognizes a ~100 kD transmembrane glycoprotein domain known as CD166 (the CD6 ligand) or the Activated Leukocyte Cell Adhesion Molecule (ALCAM). CD166 belongs to the immunoglobulin superfamily (IgSF) and it is widely expressed on activated lymphocytes and monocytes as well as other non-hematopoietic cells such as epithelial cells, fibroblasts and nerve cells. CD166 plays various roles in mediating physiological processes including angiogenesis, immune response and cell migration during the neuronal develop-ment. Overexpression of CD166 contributes positive indication of MM progression and that purified soluble CD166 effectively inhibits tumor progression. CD166 might be a potential therapeutic target against hematopoietic malignancy including MM.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Cultured human thymic epithelial cells
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))
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别名
- CD166
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基因ID
- 214
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UniProt
- Q13740
抗原
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