Endoglin 抗体 (FITC)
Quick Overview for Endoglin 抗体 (FITC) (ABIN7076816)
抗原
See all Endoglin (ENG) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD105 FITC Antibody
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产品特性
- The clone SN6h, a mouse monoclonal antibody selectively binds to a ~95 kDa type I transmembrane homodimer glycoprotein known as CD105. It is also encoded by END (Endoglin) and belongs to the TGF-β type III receptor family. CD105 mostly expressed on vascular endothelial cells, placental syncytiotrophoblasts, mesenchymal stem cells, erythroid precursors, activated macrophages, pre-B cells, and some tumor cells and cell lines including U937 cells. CD105 works as an important regulatory component of the TGF-β receptor system. CD105 expression is increased on activated endothelium tissues undergoing angiogenesis and also in cases of wound healing or dermal inflammation. CD105 may also be involved in the solid tumor metastasis, in regulation of cytoskeletal cellular organization as well as migration.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- EDG (CD105) isolated from acute lymphoblastic leukemia cells
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- Endoglin (ENG)
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别名
- CD105
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基因ID
- 2022
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UniProt
- P17813
抗原
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