CD21 抗体 (FITC)
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北京 101111
Quick Overview for CD21 抗体 (FITC) (ABIN7076447)
抗原
See all CD21 (CR2) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD21 FITC Antibody
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产品特性
- The mouse monoclonal antibody produced by clone HB5 binds to complement receptor 2 (CR2), known as CD21, a 145 kDa glycoprotein of the complement control protein family. It is a receptor for the complement components C3d and C3g and, under pathological circumstances, for the Epstein-Barr virus (EBV). As complement breakdown fragments remain bound to the agent initiating the complement activation in the first place, CD21 plays an important role in the uptake of immunocomplexes. In addition, it plays a role in B cell development and activation as well as memory B cell survival. Thus, it is a key component in developing and maintaining humoral immune response to T-dependent antigens. CD21 associates with CD19, CD81 and the B cell receptor. The cell surface marker CD21 is expressed on mature B cells and follicular dendritic cells. It is used as a cell marker for the phenotyping of leukemias.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Human complement receptor 2 (CR2)
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亚型
- IgG2a
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应用备注
- FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
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别名
- CD21
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基因ID
- 1380
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UniProt
- P20023
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途径
- Complement System
抗原
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